Acumetis is a global expert commercialisation partner purposefully built to help life sciences win in the age of connectivity. With an integrated model spanning the entire asset lifecycle, deep functional and therapeutic-area expertise, and rigorous, outcome-driven thinking, Acumetis reframes complex problems and shapes solutions that are both imaginative and achievable. With more than 350 experts globally and experience across 50+ geographic markets, Acumetis helps clients unlock value, accelerate performance, and deliver better outcomes for patients.

Acumetis. Reframe what’s possible.

As a Principal, you are a senior leader within the organisation, responsible for shaping strategic direction, driving commercial success, and representing Acumetis at the highest levels. Principals act as trusted advisors to senior executives across pharmaceutical and biotech organisations, guiding decisions that influence global pricing, access, evidence generation, and commercialisation.

You will lead major accounts, support long-term client partnerships, and oversee complex programmes. Principals influence firm-wide capabilities, set quality and methodological standards, and contribute to organisational strategy, growth, and culture.

This role carries significant responsibility for commercial performance. You will shape business development strategy, secure high-value opportunities, and mentor leaders across the organisation to support long-term commercial sustainability.

Principals model the highest standards of leadership, integrity, collaborative behaviour, and strategic insight. You represent the organisation externally, contribute to thought leadership, and play a central role in internal governance, capability development, and strategic decision-making. This role represents a shift from leading portfolios to stewarding the organisation, preparing you for progression to Partner, where long-term strategy, governance, and external market influence are central.

ROLE RESPONSIBILITIES AND EXPECTATIONS

Core Knowledge

• Set firm-wide strategic direction across access, pricing, HEOR, and evidence strategy.

• Establish and uphold methodological, analytical, and quality standards across all client work.

• Act as the ultimate authority on complex or high-risk strategic questions.

• Ensure the firm’s thinking remains innovative, credible, and market-leading.

How You Work

Strategic Thinking & Decision-Making

• Shape long-term strategic priorities for the firm in response to market trends and opportunities.

• Guide executive-level decision-making across clients and internal leadership forums.

• Balance strategic ambition, commercial risk, and organisational sustainability.

Quality & Standards

• Define and steward quality expectations across programmes, portfolios, and practices.

• Serve as escalation point for the most complex or sensitive client and delivery challenges.

• Ensure consistent excellence across evidence, pricing, access, and HEOR outputs globally.

Portfolio, Resource & Commercial Oversight

• Oversee the firm’s highest-value accounts and programmes, ensuring sustainable delivery and profitability.

• Shape revenue planning, forecasting, and long-term portfolio development.

• Guide investment decisions related to capability building, tools, and service offerings.

Client Leadership & External Influence

• Act as a senior trusted advisor to executive-level client stakeholders.

• Lead the firm’s most high-stakes client engagements and negotiations.

• Represent Acumetis externally through conferences, publications, partnerships, and industry forums.

What You Do

Strategic Account & Programme Stewardship

• Own and steward global or strategically critical client accounts.

• Provide executive oversight across complex, multi-country or multi-stakeholder programmes.

• Ensure client engagements deliver long-term strategic value and partnership growth.

Thought Leadership & Market Influence

• Shape and lead firm-wide thought leadership, methodologies, and strategic frameworks.

• Drive innovation in consulting approaches, tools, and offerings.

• Influence industry dialogue through publications, speaking engagements, and partnerships.

Commercial Leadership

• Lead business development strategy at firm or practice level.

• Secure and expand high-value commercial opportunities.

• Shape market positioning and long-term growth strategy.

Organisational Leadership & Governance

• Lead or co-lead major internal initiatives (capability building, practice development, strategic planning).

• Contribute to governance, investment decisions, and organisational change.

• Support long-term workforce planning and leadership succession.

People Leadership & Culture

• Provide strategic leadership for people development across the organisation.

• Own succession planning and leadership pipeline development.

• Coach and sponsor senior leaders (Directors, Associate Directors).

• Champion psychological safety, DEI, wellbeing, and inclusive leadership.

• Model the highest standards of leadership behaviour, integrity, and accountability

Career Development

At Principal level, development focuses on organisational stewardship and external influence, including:

• Deepening executive-level advisory credibility and industry authority

• Expanding ownership of long-term strategic client partnerships

• Driving commercial growth and market positioning across regions or practices

• Influencing firm-wide strategy, investment, and capability priorities

• Building and sustaining a strong leadership pipeline

• Leading thought leadership and external engagement

• Owning elements of governance, culture, and values

Progression to Partner is based on sustained high performance, proven commercial leadership, and meaningful contribution to the firm’s long-term strategic ambitions.

Qualifications and Experience

Education

• Degree-level qualification (2.1 or above preferred) in a health-related, analytical, or numerical scientific discipline, such as:

  • Health Economics, Public Health

  • Maths, Statistics, Econometrics

  • Biochemistry, Natural Sciences, Life Sciences

  • Engineering, Operational Research, MORSE

• Advanced degree (MSc, MRes, MBA, PhD) strongly preferred in:

  • Health Economics

  • Biostatistics / Medical Statistics

  • Epidemiology

  • Mathematics / Econometrics

  • Other analytical, quantitative, or health-related disciplines

Skills & Capabilities

• Extensive experience leading major consulting programmes globally.

• Recognised expertise in Market Access, HEOR, pricing, or related disciplines.

• Demonstrated success in senior commercial leadership and account growth.

• Strong experience in senior-level coaching and organisational development.

• Proven ability to shape thought leadership and influence industry discussions.

VALUE FRAMEWORK

At Acumetis, our values are built upon four essential values that define the competencies and behaviours needed for each role within our organisation: business, self, team, and client. These values are represented by: